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Cognitive and Behavioral Inflexibility in Lurcher Mice In the conditional visual discrimination task, where the condition of getting a reward were reversed after acquisition trials, Lurcher mice adjusted their behavior according to the reversed task, but still made more errors than WT mice [175]

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This lipolytic effect appears to be mediated through activation of 3-adrenergic receptors on adipocytes, which are G-protein coupled receptors that, when activated, stimulate adenylyl cyclase to increase intracellular cAMP levels